Presidential Address “Evidence-based” has become a buzzword used within many disciplines, often without full understanding of what it means and how it is linked to scientific method. Yet understanding how to identify and assess the scientific evidence available for any mental health intervention is essential to the promotion of mental health equity. As Parent–Child Interaction Therapists (PCIT), we have a legacy of rigorous studies with often-replicated findings to support our work with families. When we implement PCIT with fidelity, many families experience meaningful positive change. The PCIT literature is not without limitations, however. As with other evidence-based mental health interventions, PCIT was developed and evaluated within discriminatory systems. As clinicians, therefore, we must consider the ways in which PCIT may not meet the needs of families across all cultures, and as researchers, we must assess cultural factors that moderate outcomes for communities. We have done—and currently are doing—much of this work. However, there is an inherent tension between our desire to provide responsive services for every family NOW and the need to maintain an evidence-based approach to intervention. Dr Niec will examine both sides of this tension, highlighting areas of need in the PCIT research, and providing examples of adaptations that have met the challenge of remaining “evidence-based.” Ultimately, if we truly seek to reduce mental health disparities among underserved families, PCIT clinicians and researchers must answer the challenge of embracing the evidence, which is, at its core, an ethical challenge.